La maladie cœliaque Partie 2

Celiac disease what is it? – Part 2

What is gluten?

Latin means glue glue. This protein is an elastic mass which is found in several cereals: wheat, barley and rye (containing respectively gliadin, hordein and secalin), but also because in many foods Learn bread, biscuits, pasta and many other foods. Bakery, gluten gives a soft texture for many of the products manufactured. This is a very effective binder used in various food industries as among manufacturers of ready meals, sauces etc … In Europe and the United States, an estimated 1 in 100 is gluten intolerant.

What are the specific causes of this abnormal immune response?

Although genetic and environmental factors ((intestinal infections, trauma caused by surgery or pregnancy stress …) are involved, the medical profession does not really know the causes of this form of allergy. However, researchers have found in a family whose members are close with the probability that one is reached is nearly 10%. hereditary component has been clearly detected.

These same researchers now know which genes are involved. This is 95% of the HLA DQ2 and DQ8 category. According to them for reasons they still do not know: there would be an increased intestinal permeability in individuals predisposed to this disease. This is what allows some gluten trigger an immune response by entering the small intestine of patients that the disease does not always appear in susceptible individuals. They state that other factors come into play, even if they were not accurately detected to date.

There are complications in poor absorption of nutrients in the intestine where malnutrition especially in cases where the patient is not following the gluten-free diet.

Malnutrition therefore causes muscle weakness, many deficiencies and weight loss where the fatigue which is the most common complaints patients. Following these failures, one can also notice some other intolerances, such as lactose that usually occurs. However, it may disappear if the patient opts for a gluten-free diet.

There is also a risk of anemia when iron stores are depleted in the body. This is caused by poor absorption of iron. Some patients in poor absorption of calcium and vitamin D, it is sometimes observed losses in bone density resulting from osteoporosis.

In the series of possible complications, one can also observe that kidney stones caused by poor absorption of nutrients from the intestine which causes abnormal presence of certain wastes in the blood which oxalate (also called ethanedioate) deemed to be reasonably excreted in the feces. In excessive amounts in the blood in the kidneys and is the cause of kidney stones.

You should know that other complications, which are not necessarily related to bowel disease may exist without a real connection can be made. We see all these in the next section.

By Aissatou KOUROUMA

Téléphone: 06 95 78 72 34

Celiac disease, Gluten, Intolerance


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